Smoothing r binning bigwig plots in R
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6 weeks ago
star715 ▴ 40

What are R tools/packages I can use to smooth a bigwig plot? I basically want to get bam coverage as bigwig files for every 100bp regions. I am using rtracklayer and genomicAlignment packages to convert bam to bigwig files.

bigwig R bam • 158 views
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Check the genomation package from Bioconductor which has a ScoreMatrixBin() to load coverages from bigwig files and bin it over specific intervals.

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