How to get copy number of gene from WGS data?
0
0
Entering edit mode
2.3 years ago

I am looking specifically to find the number of copies of a single gene from WGS data.

CNV genotyping WGS • 642 views
ADD COMMENT
1
Entering edit mode

if you look for simple deletions and tandem duplications, you can run Manta on your genome.

if you consider your gene complex and polymorphic, you need several other samples to establish the baseline. more complex the gene is - more samples you need as a background, up to 500. I have not seen anything that requires more than 500 samples, but there is no limit for genome complexity.

ADD REPLY

Login before adding your answer.

Traffic: 2474 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6