Pathway analysis of DEG

Question

[bookorg]

Hi I want to find out my identified DEG pathway in R.The pathway that i wanted to generate from WIKI,REACTOME and KEGG .So i need some help to generate this pathway in R.

Answer 1

[MiladAD]

Hello

Use toppgene to find out what pathway(s) have enriched in your differentially expressed genes. another recommended pipeline for you is using WGCNA and then use your most related functional gene modules to do gene set enrichment analysis to find most precise pathways.

I hope it helps