Job:Bioinformatician in immunogenetics
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14 months ago

Job offer from January 24, 2022

The Max Planck Institute of Immunobiology and Epigenetics is looking for a Bioinformatician (m/f/d) in Immunogenetics. The position will be available in the Boehm department. The Boehm group addresses a number of cutting-edge research questions related to the development and evolution of the vertebrate immune system (for recent review see, Annu Rev Immunol 36, 19,2018; Annu Rev Anim Biosci 2, 259,2014; Nat Rev Immunol 13, 831,2013). To support these studies, we seek an experienced bioinformatician with a strong background in sequencing data analysis, statistics and, ideally, prior exposure to immunogenetics studies.

This position is open immediately and funded for two years, with the possibility of extension.

The Max Planck Institute of Immunobiology and Epigenetics (MPI-IE) in Freiburg, Germany is an interdisciplinary research institution that conducts basic research in two key areas of modern biology: Immunobiology and Epigenetics. Central questions address the molecular basis of cell type identities, as they are regulated during immune cell differentiation, metabolic response and epigenetic chromatin adaptation. Your opportunities:

As an embedded bioinformatician, you will have the opportunity to contribute directly to multiple research projects, from experimental design to data analysis and interpretation. You will interact with a strong, interdisciplinary bioinformatics and deep sequencing team that provides access to a large Sequencing Facility (HiSeq3000, HiSeq2500, NextSeq500, Oxford Nanopore), as well as a high-performance Data Center with integrated Petabyte-scale storage solutions and established data processing pipelines and analysis frameworks. Your tasks:

Responsibilities include:

  • Design of sequencing experiments
  • Processing and quality control of NGS datasets of whole genome and amplicon bisulfite sequencing
  • Discovery of differentially methylated regions
  • Variant calling
  • Analysis of differential gene expression (bulk and single-cell RNA) and gene module calling
  • TCR clonotyping
  • Analyses of sequence homologies and conservation
  • Reference genome and transcriptome assembly and annotation in non-model organisms
  • Phylogenetic and comparative genomics analyses
  • Development and implementation of custom analysis pipelines in collaboration with wetlab scientists

Your qualifications:

We are looking for a dedicated and motivated team player with strong communication skills and good command of the English language, holding a MSc or PhD degree in bioinformatics or biology with a clear computational component. The successful applicant will have a proven record in the analysis of large, high-dimensional genome-wide datasets and computational skills (Python or R) in a Linux environment. Additional pluses include experience in the following:

  • High-performance computing in a cluster environment (e.g. slurm)
  • Modern software development, deployment (conda), and version control (git)
  • Workflow management (snakemake) and documentation (notebooks)
  • Advanced statistical data analysis

We offer:

Located in a region that connects Germany, France and Switzerland, our institute offers an international research environment with outstanding infrastructure facilities and a positive working atmosphere that places a high value on work-life balance.

  • Salary according to your qualification and professional experience according to TVöD
  • Social benefits in line with public service
  • Professional training and development opportunities
  • Challenging work in a modern working environment
  • Family-friendly offers (affiliated day care center at the institute, parent-child room, breastfeeding room, pme family service)

We value and promote diversity, inclusion and equal opportunities, so we welcome applications from all backgrounds. We particularly welcome applications from severely disabled people. We would also like to increase the proportion of women in areas where they are underrepresented and therefore expressly encourage women to apply. Application deadline:

Have we sparked your interest? Please submit your complete application documents including a 1 page motivation summary, CV and contact details of referees via our online application portal by March, 31st, 2022. For informal inquiries please contact: boehm [at]

Max Planck Institute for Immunobiology and Epigenetics, Ms. Schätzle-Ott, Stübeweg 51, 79108 Freiburg, Germany

immunogenetics mpi • 415 views

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