Chip-seq intersect TSS

Question

[Morris_Chair]

Hello Everyone, I have two Chip-seq performed with two different proteins and I have to generate a heat map binned 5Kb around the TSS for one of them and see wether the second protein binds into the same region but I don't know which tool to use. Do you have any advice on what's the best way to do that? Is the R package EnrichedHeatmap ok for it?

thank you in advance

[ATpoint]

I wrote a small code chunk / tutorial some years ago that you might use for inspiration: Using EnrichedHeatmap for visualization of NGS experiments

Is this what you need?

[Morris_Chair]

Hi ATpoint thanks for the answer, The heat map in your tutorial is only for a protein and that's the first thing I would do but I want to see if another protein (from a second independent ChIP-seq) binds into the same regions or at least which binding regions are in common.

Ideally what I would but but I don't know if it is feasible, two heat map like in your tutorial binned for the TSS and intersect them to show TSS in common