Entering edit mode
2.2 years ago
Dan
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0
I am interested in seeing the distribution of Cadd scores for all missense mutations of a given gene. My understanding is that version 3.1 of GnomAD provides each variant with a Cadd score.
Is there an efficient process for isolating out the Cadd score from GnomAD database?
You don't need to use GnomAD, use VEP instead ( https://www.ensembl.org/info/docs/tools/vep/index.html ) UPD: sorry it is not done by default, this plugin does https://github.com/Ensembl/VEP_plugins/blob/release/105/CADD.pm
Damn thanks for this, there was me downloading the entire CADD database and setting up a very awkward pipeline to grep out the correct SNPs!