Gene Annotation after EdgeR in R

Question

[saamar.rajput]

Dear All,

I have an EdgeR analysis for Human genes. Now I want to add the annotation for all individual genes in a column against the genes. Is there a package in R that takes a list of genes and generates the annotation against each gene?

Thank you in advance!

[ATpoint]

What do you mean by "annotate"? If you want functonal enrichment check the gprofiler2 package or its GUI:

https://biit.cs.ut.ee/gprofiler/gost

https://cran.r-project.org/web/packages/gprofiler2/index.html

[saamar.rajput]

I am sorry it was not clear enough, but i want functional annotation for every single gene. Like what is the function of this one gene, i want this for a list of genes.

[ATpoint]

This does not exist I think in the way you imagine it. You cannot enrich a single gene for anything, and a gene's function can be diverse depending on cellular context. You can pull out simple gene descriptions with tools like biomaRt, but for enriched terms you need to provide gene lists that then are to be compared to annotated pathways and processes. After all there is manual literature work to be done to interpret your results.