I have multiple vcf of CASES and CONTROLS variations annotated by VEP, SNPEff, SnpSift.
first pair vcf -> only variations| CASES and CONTROLS second pair vcf -> variations + SnpEff | CASES and CONTROLS third pair vcf-> variations + SnpEff+VEP+SnpSIFT| CASES and CONTROLS | at so on
Because it have non-overlapping samples, i tried to merge corresponding vcf of CASE and CONTROLS into one file with bcftools merge.
bgzip -c file.vcf > file.vcf.gz tabix -p vcf file.vcf.gz bcftools merge -o merged.vcf.gz -Oz file.vcf.gz file_2.vcf.gz
Unfortunatelly in files with SnpSift annotations i got this error:
Error at chr1:20724637: wrong number of fields in dbNSFP_ada_score?
Please anybody knows how to solved this error or what does it mean?