Entering edit mode

2.2 years ago

mropri
▴
150

Hi,

I have a matrix of protein expression that has some missing values. I know its MNAR (missing not at random). However, I am having trouble using the impute.QRILC command to impute the matrix as I get the same matrix as a result. Would someone be able to me understand why the matrix is not imputing? My code is the following:

```
y_qrilc <- impute.QRILC(norm_prot)[[1]]
```

`norm_prot`

is my protein expression matrix

Any help is appreciated.

Are you getting any error messages? I had issues installing the imputeLCMD package in both Linux and Windows. Can you use another imputation method, such as k-nearest neighbor?

Yes, I was getting error messages. However, I was able to install imputeLCMD package and run impute.QRILC but was getting the same matric back. Would k-nearest neighbor be acceptable method for values that are not missing at random?