Integrate scRNAseq with 10x Multiome

Question

[fmazzio1]

Hello,

I have a question that may be a bit naive :)

I have six 5' scRNAseq samples. We are planning to run 4 samples with the 10x Multiome scATAC + RNA seq to look at the transcriptome and epigenome.

I was wondering if it's possible to then "extract" the transcriptome data from the Multiome and integrate it with the six scRNAseq samples to add up to a total of 10.

Thanks!

Francesco

Answer 1

[mikhael.manurung]

Yes, it is possible. You just need to keep in mind you have to take into account the different technologies that were used.