Entering edit mode
23 months ago
cdeantoneo31
▴
20
First I am a huge noob to bioinformatics and most of my knowledge is self taught, so please excuse my lack of vocabulary and just overall dumbness
My PI would like us to compare survival of cancer patients who have knock out/loss of function mutations in gene a, ko/lof in gene b, and fully functional gene A with ko/lof gene b.
My question is: what is the best way to do this? Should I use R and the TCGA R tools, or is there a more user friendly tool?
I have not done this myself, so please take with a grain of salt. I looked around right quick. The "TRGAted" platform appears to perform survival analysis on TCGA data. Check out this article and let me know what you think. Does it help at all? If not, why not and we can go from there
more generally, definitely read the linked wikipedia page on survival analysis. not sure if you have a math or stats background. if not, parsing the notation is non-trivial at first. but irrespective, even if you only understand a fraction of it, will be worthwhile
Will do, tysm!
This actually is super helpful, thank you!
My B.S. is in biochemistry, so not super heavy math or stats, but the wikipedia page is definitely understandable