GnomAD subset vcf files
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22 months ago
kanika.151 ▴ 130

Hello All,

Do you know how to extract variants related to a specific population from the GnomAD exome vcf file?

In ExAC, one can find subsetted vcf files for non-TCGA and non-psych population. But, I wanted to get subset vcf file for 'Controls-only' from GnomAD exome file. Is there a way?

Also, there is this comment in the README file:

Filtering allele frequency (FAF) annotations: for any variant that occurs as a singleton in a population, the population-specific FAF should be 0. We have amended all FAF annotations accordingly.

Does this mean that if for a population FAF is zero then it only exists in that population, right?

Thank you all.

exac gnomad population vcf subset • 453 views
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