Deleted:Unbiased approach for enrichment analysis?
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10 days ago
kgoss ▴ 10

I'm trying to come up with a way to perform an unbiased enrichment analysis on my scRNAseq data. For example- In my particular analysis, there are over 300 pathways returned. How do I go about sifting through these pathways without a biased lens - i.e. not just go pick the pathway(s) that I'm interested in or have looked into before, but instead find something that is truly biologically relevant and possibly novel? I considered filtering based on p value, or number of genes in my dataset that are included in the pathway, or something else. Any suggestions?

GSEA scRNAseq transcriptomics • 105 views
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