Cell Type and Gene Specific Survival Analysis in scRNA-seq
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22 months ago
Ergün ▴ 20

Hi Biostars Community,

As I understand, TCGA is composed of bulk RNA-seq data from various cancer types. Is there an opportunity to perform survival analysis based on the expression of a gene that is specific to a cell type (e.g. how do cytotoxicity markers in T cells but not in NK cells affect the cancer survival)?

There are some computational methods for deconvolution of bulk RNA-seq data. However, is there a scRNA-seq related cancer cohort database?

Thank you in advance,

TCGA scRNA-seq • 344 views
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