ESTIMATION OF LEVEL OF CYTOKINES FROM BULK RNAseq
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6 weeks ago
leticia ▴ 20

I am working on RNAseq analysis (TCGA ) , i use cibersorts to analyse immune cells fraction in two conditions. i was wondering if it is possible to estimate the level of cytokine from Bulk RNAseq especially after analyzing it on Cibersort ?

thank you in advance

rnaseq r tcga bulkrnaseq • 218 views
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6 weeks ago
Rafael Soler ▴ 460

Hello Leticia,

I don't know much about Cybersort analysis, but you can check genes related to cytokine activity GO Term http://www.informatics.jax.org/vocab/gene_ontology/GO:0005125 or cytokine production GO Term http://informatics.jax.org/vocab/gene_ontology/GO:0001816 to find how many cytokine-related genes are expressed under the two conditions.

Best,

Rafael

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