I have sequenced 4 MRSA genomes. If I want to perform pan genome analysis for them, are they enough by themselves or do I need to add more MRSA genomoes from NCBI?

Question

[Jaykumar]

I have sequenced 4 MRSA genomes. If I want to pan genome analysis of them, are they enough by themselves or do I need to add more MRSA genomoes from NCBI?

[GenoMax]

Posting your entire question as the title and then repeating it in the body of the post is bad etiquette. Please edit the post and post a concise title.

Answer 1

[Joe]

You need more.

[Joe]

Less bluntly: it depends on the question you're asking, but I can't really think of a question worth asking where only 4 genomes will satisfactorily answer it where pangenomes are concerned.

[Jaykumar]

Okay. Thank you!!