Constituent enhancer .gff for ROSE algorithm from dREG output
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2.0 years ago
c.heininger ▴ 10

Hi everybody,

I am trying to use the ROSE algorithm by Young Lab to identify super-enhancers within our novel PRO-seq dataset. I have used dREG to call enhancers from each sample of the PRO-seq dataset and the output is a bed file of identified enhancers. My question is, could I use this bed output as the constituent enhancer file that ROSE requires for the super-enhancer calling? If so, how do I convert this bed file into a gff file for ROSE?

Any help is greatly appreciated!

super-enhancer enhancer dREG ROSE • 463 views

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