Irreproducibility Discovery Rate for broad histone marks.
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4 months ago
tsomakiank ▴ 40

Hello, I have to run the idr framework on some .broadPeak files. Is it appropriate to run idr on broad peaks or the framework only applies to narrow marks? Thanks in advance!

chip-seq idr • 183 views
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Entering edit mode
4 months ago

IDR is ideal for narrow peaks.

You can run it on broad peaks but it doesn't seem to be advisable (overly conservative):

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