Entering edit mode
18 months ago
WubbaLubbaDubDub
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0
Why does megablast have a lower gap cost than blastn? since we have long alignments, dont we also have a bigger number of gaps compared to the short alignments of blastn? Also why are we "bothered" by low complexity regions? I get that they give a higher score but arent they important for homology, therefore should be included?