Basic question: I have summary stats from a GWAS and want to derive a PRS score from them. I don't have access to the original genotype data used to do the GWAS. Is that possible without genotype information? Is there a tool to do that?
Further info: The data is presented as thus:
ID OR OR_se OR_95L OR_95U PVAL
rs309431 0.988757 0.017380 0.953108 1.022454 0.471168
I have looked at this: https://privefl.github.io/bigsnpr/articles/LDpred2.html#computing-ldpred2-scores-genome-wide
What I don't understand is, where do I use the 1000 genomes LD data and where do I "extract" the derived score to run on my own data?