Statistical test for genomic annotation by ChIPseeker
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8 weeks ago

I am performing peak annotation using peakAnno() in ChIPseeker. It works well. I was wondering if there is a way in ChIPseeker to do any statistical comparison for the overlap of peaks with the different genomic regions (i.e. intron, exon, utr, distal intergenic). This would provide an accurate analysis of relative over-/under-representation since things like distal Intergenic regions make up the majority of the genome. A proper statistical test would rule out the bias due to predominance of specific elements.

statistics ChIPseeker PeakAnnotation • 187 views
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There is the enrichPeakOverlap function that perform statistical analysis , so you could read more into this function.