Human Technopole (HT) is a new interdisciplinary life science research institute, created and supported by the Italian Government, with the aim of developing innovative strategies to improve human health. HT is composed of five Centres: Computational Biology, Structural Biology, Genomics, Neurogenomics and Health Data Science. The Centres work together to enable interdisciplinary research and to create an open, collaborative environment that will help promote life science research both nationally and internationally.
HT is looking for 2 bioinformaticians for the Centre for Neurogenomics, respectively in the CEll REference BRain Atlas (CEREBRA) Scientific Support unit and the Software Development and Data Curation Scientific Support unit.
The Software Development and Data Curation Scientific Support Unit develops, implements and maintains state-of-the-art computational tools for the analysis of data generated by cutting edge biological applications. In particular, the unit focuses on the development and implementation of pipelines for transcriptomics/epigenomics data processing, including single cell multiomics, by orchestrating the software components for data analysis and by maintaining software platforms for interactive data analysis and visualization. The unit will design and develop novel quantitative models based on the integration of high resolution multiomics and clinical data. The successful candidate will be involved in the development and implementation of high-performance computational solutions to deploy novel statistical methods for the analysis of single-cell data, including transcriptomics and epigenomics analyses, differentially expressed and regulated genes, developmental trajectories, cell populations, and clinical metadata.
CEll REference BRain Atlas (CEREBRA) Scientific Support Unit is a team with expertise in bioinformatics and neuroscience, with a special focus on innovative computational approaches for the annotation, analysis and integration of single cell multiomics data related to the human brain and its disease-associated experimental models. CEREBRA will bring together and integrate publicly available and in-house generated single cell omics brain and brain organoids datasets, enabling their fluent accessibility to researchers through the generation of bespoke data portals, streamlining their cross referencing by integrated and joint analysis in a reference atlas.The successful candidate will be involved in the setting-up, maintenance and constant evolution of a Reference Atlas of single cell multiomics data from the human brain and brain organoids, contributing to the generation of a key resource to streamline the interrogation and interpretation of experimental results related to the development and function of the human brain in physiological and pathological conditions.
Further details at this link: https://careers.humantechnopole.it/o/bioinformaticians-neurogenomics-centre