log2(TPM+1)
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17 months ago
Lakshmi ▴ 20

Hi, I have a basic question with CCLE expression data. Why is the expression data given as log2(TPM+1) instead of log2TPM?

Thanks in advance for your help.

TPM expression • 880 views
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Entering edit mode
17 months ago
Mensur Dlakic ★ 27k

Any logarithm of zero is undefined. Adding 1 to TPM values ensures we are not attempting to take log2(0).

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