I have a bed file with genotype data for around 450000 SNPs and 700 samples. I am performing a logistic regression analysis in PLINK with the option "adjust" to obtain the genomic inflation factor. It gives me a lambda of 1. However I expected a higher value since I have controls from different Spain areas. In fact, if I perform a simple association analysis (--assoc), I obtain a lambda of 1.10. Has anybody an idea of what can cause this difference between the two analysis?
Question: Genomic Inflation Factor Lambda Too Low
5.4 years ago by
mangeles.suarez • 20
mangeles.suarez • 20 wrote:
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