champ.norm error

Question

[bioLearner]

I am running a methylation data analysis using ChAMP package. I did champ.load from .idat files and now am trying to do champ.norm with BMIQ method and get the following error:

Error in champ.BMIQ(beta[, x], design.v, sampleID = colnames(beta)[x],  : 
  task 165 failed - "need at least 2 points to select a bandwidth automatically"

How do I fix it?

[Basti]

Could you check colSums(is.na(beta)) ?

[bioLearner]

Yes! I checked

sum(is.na(myLoad$beta)) 
any(myLoad$beta == 0)

and there were none