fcoex co-expression analysis
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8 weeks ago
conarial ▴ 10

Hi, I am currently analysing scRNA seq data with fcoex and I have run into a (probably quite simple) problem: can I "force" the package to analyse certain genes by name? I am especially interested in the genes that correlate to Myc in my dataset, but with the default values, Myc is not included in any of the fcoex co-expression modules.

Could anybody help me out here? Thanks :)

single-cell scRNA coexpression fcoex • 368 views
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If Myc is not included in any module what does that mean?

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I guess that Mycs correlation is not significant/prevalent enough under the filter parameters that I am using. I just wanted to ask, whether you could calculate a co-expression network for a specific pre-defined gene

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Just to clarify, co-expression networks are built from correlation measures calculated between all genes (All vs All).

I just wanted to ask, whether you could calculate a co-expression network for a specific pre-defined gene

1 (Myc) vs All is not a co-expression network

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what would that be called then?

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