Job:Postdoctoral fellow in bioinformatics - ULB (Belgium)
0
0
Entering edit mode
6 weeks ago

https://www.linkedin.com/jobs/view/1022208744

The Laboratory of Experimental Gastroenterology at the Université Libre de Bruxelles (ULB), Brussels, Belgium, is recruiting a Postdoc in Bioinformatics.

JOB DESCRIPTION

Our research focuses on discovering chronic liver disease's environmental and genetic determinants, particularly on the development of liver cancer and cirrhosis-related complications. We mainly utilize genomics and single-cell transcriptomics data. The successful applicant will take a lead role in this setting and work on a large-scale EU-funded project. More specifically, the aim will be to identify novel human genetic variations and other environmental risk factors predisposing to hepatocellular carcinoma development.

Duration: 1 year full-time with a possibility for prolongation of up to 5 years.

Starting date: As soon as possible till a suitable candidate is found.

ABOUT US

The ULB has a reputation for excellence in basic and applied biomedical research and is an active member of the European Research Area https://www.ulb.be/en/ulb-homepage. The ULB is involved in almost 80 EU-funded projects. The Laboratory of Experimental Gastroenterology is a translational research team within the Gastroenterology, Hepatopancreatology, and Digestive Oncology Department of the Hôpital Universitaire de Bruxelles, Brussels, Belgium https://www.hubruxelles.be/en. The group, led by Prof. Eric Trépo, uses genome-wide association studies (GWAS) and single-cell genomics to identify risk factors, better understand the pathophysiology of chronic liver diseases and pinpoint potential therapeutic targets [1-3].

[1] Trépo E, et al. Common genetic variation in alcohol-related hepatocellular carcinoma: a case-control genome-wide association study. Lancet Oncol. 2022;23:161-171

[2] Trépo E, et al. Combination of gene expression signature and model for end-stage liver disease score predicts survival of patients with severe alcoholic hepatitis. Gastroenterology 2018;154:965-975

[3] Buch S, et al. A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis. Nat Genet. 2015;47:1443-1448

RESPONSIBILITIES

  • Use state-of-the-art and novel computational strategies to identify environmental risk factors and genetic variants linked to liver cancer/cirrhosis complications.
  • Analyze GWAS and single-cell datasets.
  • Support research and development activities within the group.
  • Maintain accurate and detailed records of research activities.
  • Support the group leader in the management of a large-scale EU-funded project.
  • Support the group leader in training new group members.

REQUIRED QUALIFICATIONS

  • Ph.D. in Bioinformatics, Computational Biology, Physics, Engineering or equivalent.
  • Programming experience with R and Python.
  • Expertise in analyzing GWAS and associated tools (e.g., PLINK, METAL).
  • Expertise in analyzing single-cell datasets (transcriptomics, metabolomics, …).
  • Training and/or expertise with whole exome/genome sequencing is a plus.
  • Strong organizational and record-keeping skills.
  • Enthusiasm to work in a multi-disciplinary, collaborative environment.
  • Proficient written and spoken English language skills.

WE OFFER

  • A highly motivated multidisciplinary research team including biologists, bioinformaticians, and clinicians and the possibility to participate in international collaborations.
  • A salary of approximately 2500€ after-tax - commensurate with experience - and social benefits (e.g., health coverage, social security, etc.).
  • Mentoring and career development opportunities.

Applications should be sent with a cover letter, Resume/CV, and at least two references directly to Mr. Eric Quertinmont at eric.quertinmont@ulb.be and Prof. Eric Trépo at eric.trepo@ulb.be.

Read more about the post and apply online:

Application deadline: Until the position is filled.

Belgium • 384 views
ADD COMMENT

Login before adding your answer.

Traffic: 2453 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6