Likely some of you has come across such a thing when browsing around DNA or AA sequence, but unfortunately I could not find any resource that explains it.
I am cross-checking AA sequences between Genome Browser and NCBI platforms, using reference hg19/GRCh37, and have found quite a few discordant sequences between the two. More precisely, different AA's for the same position.
Here are some examples:
Transcript ID Position AA (Genome Browser) AA (NCBI) NM_000937 chr17:7417086 A T NM_001145468 chr22:24717850 D G NM_001190441 chr19:40149297 L H NM_001291324 chr17:79409366 G R NM_005126 chr3:24006477 L M
Also a question associated to that: I understand that when transcripts change their version (e.g. NM_001013356.2 to NM_001013356.3), some single nucleotides also change their sequence. What would be the explanation for that? Would that be because their allele frequency is more representative of a population (based on the ever growing studies with DNA sequence)?