Entering edit mode
9 weeks ago
lumos • 0
I am trying to find cis nature of regulatory regions. Currently, I have used a hypergeometric test for checking targets affected in the cis window versus the rest of the Genome. I have also looked at null distributions.
Is there any other approach you might be aware of to increase the sensitivity while checking whether a region has cis-regulation of nearby genes or not?
(I have expression information of all the genes when the region is knockdown)
Thanks a ton!
Hi lumos. It is not very clear to me what kind of information are you using for the test and how are you measuring cis-regulation. Are you using eQTL analysis? Allele specific expression?