Meta-analysis of rare variant SAIGE-GENE output for WGS data

Question

[tacrolimus]

Dear Biostars,

What are some recommended tools either in linux command line or R that people use to meta-analyse rare-variant gene burden analysis generated from whole genome sequencing data?

I have summary stats from two separate case-control cohorts with gene-level P-values and betas but not the individual variants that make up each gene. These were generated using SAIGE-GENE.

RARE-METAL seems to require variant level info so I am not sure it is the right one to use...

All the best