Anti-miRNA oligonuclotide identification

Question

[singh.bioinfo]

Hello everyone,

I am keenly interested to know about how to identify anti-miRNA oligonucleotide using in-silico approach. Is there any method or tool for do it. Plz guide me.

Waiting for the response. Thank you,

Sakshi

Answer 1

[Asan Emirsale]

You should find complementary sequences to make the miRNA silent. Should it be the Biopython or another tool. The solution might be as simple as mirna_seqrecord.reverse-complement() How did you chose this problem since you had described it near 6 yers ago?