Entering edit mode
14 months ago
100dustedclays
▴
10
I am still a little confused on how Genbank annotates its genes.
For example, if I look at this gene: LOC110845878 [ Folsomia candida ]
, NCBI will list it as uncharacterized.
However, if you scroll down and look at the general protein information, it calls it a pyruvate kinase PKLR.
So in this case, it would be fair to just consider the LOC110845878 uncharacterized gene as pyruvate kinase PKLR?
About
LOC
gene designation (From LINK):As for
If you trust the annotation provided by the submitter (VU Amsterdam) then yes. NCBI has not yet done their due diligence for it.
Thank you. That makes a bit more sense now.
So LOC110845878 will continue to be labelled as uncharacterized until someone at NCBI personally verifies the annotation?
LOC
designation in this case is actually coming from Ensembl's rapid release of genomes but the intent is more than likely the same as one from NCBI. Until some validation occurs this ID will stay as LOC. But it should remain searchable in future if you want to use it for something.