Are there any papers that have both anatomical imaging data and variants?
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13 months ago

Can be in any species. Data must be open access.

vcf imaging • 464 views
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Entering edit mode
13 months ago
LChart 3.9k

You know full well this is a hard ask. There are many papers in humans performing GWAS for brain regional volumes, cardiac MRI features, cranial shape (etc); but the open access requirement throws all of that away since you need (at least) dbGAP access to obtain genotype-level data. For model organisms - these are all inbred, so any studies would either be in engineered lines (in which case variant-level data is unnecessary) or crosses. This basically narrows it down to one genotype resource: the collaborative cross / diversity outbred project (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633285/).

Searching for "collaborative cross" "diversity outbred" "imaging" on google scholar yields: https://academic.oup.com/g3journal/article/11/5/jkab079/6171186

But the imaging is only from founder populations.

So I'm pretty sure the answer is no.

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