How to deal with the probe id mapping to multiple gene ids?
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15 months ago
DareDevil ★ 4.3k

I am doing a microarray data analysis based on Affymetrix Human Genome U133 Plus 2.0 Array. I have found certain probe id has got multiple gene ids. How to select the appropriate gene for that particular probe id?

207739_s_at : GAGE1; GAGE12B; GAGE12C; GAGE12D; GAGE12E; GAGE12F; GAGE12G; GAGE12H; GAGE12I; GAGE12J; GAGE13; GAGE2A; GAGE2B; GAGE2C; GAGE2D; GAGE2E; GAGE3; GAGE4; GAGE5; GAGE6; GAGE7; GAGE8

207086_x_at : GAGE1; GAGE12B; GAGE12C; GAGE12D; GAGE12E; GAGE12F; GAGE12G; GAGE12H; GAGE12I; GAGE12J; GAGE13; GAGE2A; GAGE2C; GAGE2D; GAGE2E; GAGE4; GAGE5; GAGE6; GAGE7; GAGE8

208201_at : DBET; DUX3; DUX4; DUX4L1; DUX4L2; DUX4L24; DUX4L3; DUX4L4; DUX4L5; DUX4L6; DUX4L7; DUX4L8; LOC100133400; LOC100287823; LOC100288289; LOC100291626; LOC652301

Similarly many more ids

match microarray affymetrix probe gene • 1.1k views
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similar question here, here and here

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Where are you seeing this? Platform file for this array on GEO has these names uniquely assigned.

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GenoMax I have used the same platform file only. If you look at probe id and their corresponding Gene Symbol or ENTREZ_GENE_ID you can see they are mapping multiple genes

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