I wonder if any of you can help me answer my questions. I'm trying to verify CNV for our small targeted panels to use in our lab. I have run 8 samples through ExomeDepth CNV via Congenica (4 females, 4 males) and noticed that my samples tend to pick the same references despite the fact I have supplied more than 20 sex-matched references for each sex. Is this because these reference cases just happen to the first on the list when ExomeDepth creates an aggregate reference? Are these references particularly good and therefore always picked?