vcf file download

Question

[Hriday]

I want to download dbSNP vcf file (version 155) where allele frequency (AF) for all the listed sites are present in the INFO field of vcf file. How to download?

Please help

Answer 1

[GenoMax]

From: https://ftp.ncbi.nih.gov/snp/archive/b155/VCF/

Files with .25 in name are for GRCh37 and ones with .39 are for GRCh38. No AF though.

[goodyeast]

how do you know which is which?

[GenoMax]

From the README file included in current release (https://ftp.ncbi.nih.gov/snp/archive/b157/00readme.txt )

/VCF               RefSNP VCF files for GRC (Genome Reference Consortium) human assembly
                   37 (GCF_000001405.25) and 38 (GCF_000001405.40). Files are compressed
                   by bgzip and with the tabix index.