Match variants for allele frequency, LD score, and other features
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3 months ago
Jautis ▴ 530

Hello, I'm wondering what's the best way to create a feature-matched set of variants. For example, I have set X of eQTL and I want to compare them to non-eQTL sites with the same allele frequency, LD score, and the gene's expression level. I could do something crude like define bins for each feature and for each eQTL select a non-eQTL from the same set of bins, but I'm wondering if there's a more efficient and accepted way to do this. Thanks in advance!

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