Interpretation of mean-variance trend in voom
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8 days ago
Ivana • 0

Dear biostars-community!

I am still very new to the field of RNAseq analysis and I struggle with interpretation of the mean-variance trend. Specifically, I am not sure whether I can continue with the analysis based on my "voom plot" (see below). Can anyone help me with the interpretation? I have read the corresponding papers and done the tutorials but I still feel unsure about what the mean-variance trend is about and how to correctly filter my counts table.

If you have any references or tutorial that you can recommend, I would highly appreciate it!

Thank you so much!

Best, Ivana

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