I have been trying to understand from the ANNOVAR documentation and other sites the steps needed to make these files from NCBI available to ANNOVAR. I admit to being new to bioinformatics, but have been a software developer for 30+ years. My goal is to annotate by hg38 based VCF file but do not even have a lead as to what to do with the downloaded files. From what I can tell, convert2annovar doesn't support these.
I downloaded because all of the files on the ANNOVAR download site are almost a year old and I am trying to help determine the gene(s) for a genetic condition for which the genes are not yet known - so the latest and greatest information seemed appropriate.
Thanks for any help. References to other resources would be most welcome. I am happy to learn, but have come up empty using web searches.