Entering edit mode
10 months ago
Sara
▴
270
I am trying to analyze scRNAseq
data and perform marker detection
and DGE analysis
comparing different conditions. to do so I filtered out some sets of genes including sex chromosome
related ones and mitochondrial
ones. do I need filter out Ribosomal protein genes
(starting with "RP")? what else should be filtered out?
Why do you think that anything should be filtered by category? High expression of these genes might indicate ongoing processes that define a cell. You should remove genes with very low counts or those only expressed in few cells.