Most Different Alleles Of A Single Gene

Question

[grigory.sapunov]

What is the most spectacular example of two alleles of a single gene do you know, when such alleles are significantly differ in their nucleotide sequence?

[Devon Ryan]

The HLAs can be pretty variable, so I'd probably use them as an example if that's what you need.

[grigory.sapunov]

Thanks! Good idea