Question: Phylogenetic History Of The Main Mouse Strains?
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gravatar for 2184687-1231-83-
7.7 years ago by
2184687-1231-83-4.9k wrote:

After some googling around, I've not been able to find a good reference for the phylogenetic history of the different mouse model strains. So, I've been told that BL6 and A/J both come from a cross between Mus musculus musculus and Mus musculus domesticus and they were independently derived after that common cross.

Does anybody know where I could find out more about the origin of these and other mouse strains?

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ADD COMMENTlink modified 5.3 years ago by Biostar ♦♦ 20 • written 7.7 years ago by 2184687-1231-83-4.9k
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gravatar for Neilfws
7.7 years ago by
Neilfws48k
Sydney, Australia
Neilfws48k wrote:

I'd start from the Strains, SNPs & Polymorphisms page at the Mouse Genome Informatics website. Their resources include: lists of strain names with further links, a chart of inbred strains and a link to the Nature Genetics paper, Genealogies of mouse inbred strains.

ADD COMMENTlink modified 7.7 years ago • written 7.7 years ago by Neilfws48k
2

Oh, I love that chart. I was a post-doc at Jax when that was underway and was totally fascinated. But also--there is an online book that they have on the Origins of Inbred mice: http://www.informatics.jax.org/morsebook/ Might have some interesting additional historical framework.

ADD REPLYlink written 7.7 years ago by Mary11k
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7.7 years ago by
2184687-1231-83-4.9k wrote:

I've been told I should read this recent Nature Genetics paper:
http://dx.doi.org/10.1038/ng.847 alt text

ADD COMMENTlink written 7.7 years ago by 2184687-1231-83-4.9k
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