Question: Rfam Family Types
gravatar for int11ap1
6.9 years ago by
int11ap1420 wrote:

Good afternoon from Barcelona,

I would like to ask a little question that I cannot find on the Internet. As fas as i know, there are these Rfam family types:


Cis-reg; frameshift_element;

Cis-reg; IRES;

Cis-reg; leader;

Cis-reg; riboswitch;

Cis-reg; thermoregulator;


Gene; antisense;

Gene; antitoxin;


Gene; lncRNA;

Gene; miRNA;

Gene; ribozyme;

Gene; rRNA;

Gene; snRNA;

Gene; snRNA; snoRNA; CD-box;

Gene; snRNA; snoRNA; HACA-box;

Gene; snRNA; snoRNA; scaRNA;

Gene; snRNA; splicing;

Gene; sRNA;

Gene; tRNA;


Can somebody explain what is the meaning of one RNA sequence being classified as "Gene", and only "Gene"?

What about the Intron-type?

The Cis-reg RNAs could be classified as well as lncRNA, couldn't they?

ADD COMMENTlink modified 6.9 years ago by Neilfws49k • written 6.9 years ago by int11ap1420

Probably worth contacting the Rfam folks for this, see

ADD REPLYlink written 6.9 years ago by Hamish3.2k
gravatar for Neilfws
6.9 years ago by
Sydney, Australia
Neilfws49k wrote:
  1. I would guess that the terms following the semi-colon are sub-types of the type "Gene". So those entries classed only as "Gene" are not known to belong to any of the sub-types.

As Hamish said, Rfam help is the place for specific queries.

  1. The Intron type includes RNAs such as Group I catalytic intron (ribozymes). See the Wikipedia entry.

  2. Are all Cis-reg RNAs also lncRNAs? If not, then no.

ADD COMMENTlink written 6.9 years ago by Neilfws49k
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