Create Instances From Position Frequency Matrix

Question

[b.schaefke]

How can I create instances from a position frequency matrix (in a transfac format motif) using the biopython motifs (not the old Motif) package and search for their occurence in a given sequence?

[Pablacious]

Why would you want to search for a random instance of the motif instead of the whole motif? Using the motif to search is more sensitive than an instance.