Question: somatic mutations from WGS of CGI
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gravatar for kanwarjag
5.6 years ago by
kanwarjag1.0k
United States
kanwarjag1.0k wrote:

I understand that somatic mutations occur during the development of cell and are not  transferred from one generation to other.

I analyzed a whole genome  seq data  It showed me that there are 30 variations which  are specifically somatics in matched tumor vs normal . Of these, 30 only 1 is in exonic region rest are in either promoter, intron, UTR regions. I could not find out how somatic mutations are identified in non exoinc regions. In such case are non exonic mutations with somatic status may be equally valuable or not.    

somatic mutations • 1.4k views
ADD COMMENTlink modified 4.7 years ago by Biostar ♦♦ 20 • written 5.6 years ago by kanwarjag1.0k

What was the approach that you used to identify the somatic mutations?  What is your question?

ADD REPLYlink written 4.7 years ago by Sean Davis25k
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