I am newbie in Bioinformatics. I have downloaded all the bacterial genomes (all.fna) from
I have some questions about the genomes and I will be appreciated if you help me to find the appropriate answer.
Are the bacterial genomes for a single strand or double strand?
In case of single strand how can I obtain the inverse strand. Should I start to read from the last letter in the genome and change the letters A --> T, C-->G, G-->C and T-->A, or its not a matter if I start from the first vs last letter in the genome?