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Forum: Hand-waving Multidisciplinary Aspects of Research Projects (Discussion)

ethics forum discussion research publications written 22 months ago by Spencenerd • 10 • updated 22 months ago by John ♦ 12k

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Forum: Finally the much awaited DAVID update has taken place. Thoughts in the community will be appreciated

david forum gene ontology discussion go written 2.5 years ago by vchris_ngs • 4.6k • updated 2.5 years ago by Pierre Lindenbaum ♦ 115k

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Forum: “Systematic pattern of excess success"

discussion forum paper statistics written 4.0 years ago by mikhail.shugay ♦ 3.3k • updated 4.0 years ago by Gregory.Francis • 20

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Forum: Is Bioinformatics a creative field/industry?

forum discussion written 4.0 years ago by 14134125465346445 • 3.4k

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Recent Replies

C: Suggestions needed for mIRNA-human target prediction ? by k.kathirvel93 • 150
I have different number of Target genes from those three DBs(150 from miRDB, 205 from miRwalk), I...
C: TargetScan search for miR-10b-5p by Kevin Blighe ♦ 33k
It seems AOK (all okay) for me. Can you confirm what you are doing to obtain the "*Prediction fil...
C: Count the number of homozygous and heterozygous variants in VCF file by finswimmer ♦ 8.0k
Could you please post a small example of your file and the output you get and which you would exp...
C: GATK 4 Mutect2 gives too much low depth variants by Kevin Blighe ♦ 33k
Maybe these are down-sampled 'high quality' reads? The actual position read depth may be higher. ...
A: Suggestions needed for mIRNA-human target prediction ? by Kevin Blighe ♦ 33k
Hey, Here is the way that I did it: #1, *in silico* predicted gene targets In order to identif...
C: FPKM quantile normalization by Maryam • 40
Do you mean for example log transformation?
A: Interpretation of TCGA clinical data by kristoffer.vittingseerup • 1.0k
I would suggest to use the data provided by the TCGA CDR (Clinical Data Resource) which have been...
C: Suggestions needed for mIRNA-human target prediction ? by kristoffer.vittingseerup • 1.0k
I don't understand you problem? You have a list of DE miRNAs and you have a list with the predict...
C: Count the number of homozygous and heterozygous variants in VCF file by WouterDeCoster ♦ 35k
I added code markup to your post for increased readability. You can do this by selecting the text...
C: FPKM quantile normalization by kristoffer.vittingseerup • 1.0k
You probably need some additional transformation to make it suitable for modeling - the distribut...
C: How to judge MSA from tree? by jrj.healey ♦ 9.1k
Deciding which alignments are best is still quite subjective. You might be most interested in an ...
A: Count the number of homozygous and heterozygous variants in VCF file by aadhirareddy1323 • 20
cat vcffile \ | perl -ane ' /^#/ and next; %c = (); foreach (@F[9..$#F]) { /^...

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