0
votes
0
replies
206
views
Recent Votes
Recent Locations •
All
Hong Kong, just now
Netherlands, 1 minute ago
Bologna, 1 minute ago
Netherlands, 3 minutes ago
Somewhere, 5 minutes ago
Deutschland, 5 minutes ago
United States, 6 minutes ago
Recent Awards •
All
Popular Question to
zx8754
11k
Popular Question to
xiaoguang
▴
120
Popular Question to
luffy
▴
30
Popular Question to
blz
▴
10
Popular Question to
Ram
40k
Popular Question to
mohammadhassanj
▴
260
Recent Replies
Answer: Importance of Data Structures for Bioinformatics?
by
xiaoguang
▴
120
Bioinformatics is a cross-disciplinary research subject and learning anything is a plus for future participation in related jobs. But right…
Answer: How to find positions with higher depth relative to their surroundings
by
xiaoguang
▴
120
I saw you want to get regions that have significantly higher depth than their surroundings; you must get a p-value to show significant as w…
Comment: how to calculate BAF and LRR from VCF or BCF files?
by
xiaoguang
▴
120
Hi, The ASCAT new version has introduced a new function called `ascat.prepareHTS`, which can be used to prepare all files that are required…
Comment: GERP++ (gerpcol) error on a test data
by
Diana
•
0
I solved the problem in the end. I was under the impression that the reference sequence had to be provided in a separate fasta file:
c…
Answer: How to find positions with higher depth relative to their surroundings
by
d-cameron
★
2.9k
The usual way of doing this is to use one of the many existing copy number variant caller. Doing this yourself is both a) complicated to do…
Answer: How to retrieve LoF and missense variants in WES data?
by
luffy
▴
30
@ _quantum_girl_, as Pierre mentioned, you can annotate your VCF with [snpEff][1] or [ensembl vep][2] once you annotated you could filter n…
Comment: Adding a control sample to bulk RNA-seq
by
Chris
▴
180
Thank you so much! It is from the same lab but from another project. Would you please explain about combining the counts together a little …
Answer: Importance of Data Structures for Bioinformatics?
by
d-cameron
★
2.9k
> how important are Data Structures to multi-omic / bioinformatic analysis
Generally speaking, they're not critical if you are using an …
Answer: Recommended order of operations for identifying the genomic location and copy-nu
by
dk0319
▴
70
Update: The above workflow was successful, in that contig_1719 does contain approximately 4 copies of my insert based on searching pieces o…
Comment: manhattan plot with vcf information
by
sooni
▴
10
I want to find out specific genes using the manhattan plot. I divide the patients into two groups, controls and patients, and try to identi…
Comment: Importance of Data Structures for Bioinformatics?
by
dsull
★
4.6k
If you don't want to hurt your GPA, why not just take the course pass/fail or, if that's not an option, simply audit it?
I doubt anyone wi…
Comment: How to DESeq2 using miRNA data obtained using TCGAbiolinks
by
swbarnes2
13k
miRNAs are rather small, and your typical RNASeq library prep will remove small sequences. Are you sure that the data you are trying to ge…
Comment: Inflated GWAS test statistic after merging multiple batches of genotype dataset
by
LauferVA
3.7k
even these measures will very often not fix the problem in the context of a problem of a problem of perfect separation such as OP describes.
Comment: Inflated GWAS test statistic after merging multiple batches of genotype dataset
by
LauferVA
3.7k
Hi Amy, I understand, this is why I said,
> "The degree to which this is possible depends on the relative content
> of each study - e.g. …
Answer: What is the difference between norm --multiallelics -any versus --atomize?
by
Ram
40k
I don't think atomization compares to norm with respect to multiallelic sites. You can see an example of atomatization on a multi-allelic s…
Traffic: 2430 users visited in the last hour
Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by the
version 2.3.6
version 2.3.6