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3
votes
3
replies
301
views
What are accession numbers starting with PIR e.g. PIR60289?
accession_number
updated 4 months ago by 13k • written 4 months ago by ▴ 350
3
votes
5
replies
1.6k
views
What kind of systematic bias of sequencing data the following normalization procedure address?
next-gen normalization bias
updated 3.7 years ago by 36k • written 6.2 years ago by ▴ 350
28
votes
9
replies
22k
views
samtools bedcov vs. bedtools coverage
DNA-seq coverage
updated 3.7 years ago by 36k • written 6.0 years ago by ▴ 350
20
votes
16
replies
4.6k
views
Breaking down the reference genome chromosome-wise
reference_genome fasta
updated 3 months ago by 36k • written 7.6 years ago by ▴ 350
0
votes
3
replies
2.7k
views
How to create a pooled normal exome sample?
next-gen sequencing exome copy number analysis
updated 4.7 years ago by ▴ 180 • written 6.9 years ago by ▴ 350
0
votes
0
replies
1.7k
views
Best way to normalize Human BodyMap 2.0 data
RNA-Seq normalization
updated 5.8 years ago by 20 • written 6.5 years ago by ▴ 350
5
votes
5
replies
3.1k
views
what does Num_Probes in a segmentation file refer to?
sequencing
updated 6.2 years ago by ★ 2.9k • written 6.2 years ago by ▴ 350
19
votes
15
replies
4.9k
views
6 follow
What is the best way to make a bam file smaller by removing unwanted information?
next-gen bam sequencing compression
6.3 years ago by Dataman ▴ 350
6
votes
5
replies
4.1k
views
How to create B-allele frequency file for ADTEx?
next-gen sequencing exome adtex
updated 6.9 years ago by 5.6k • written 6.9 years ago by ▴ 350
11
votes
1
reply
4.0k
views
Does one need to sort and index after performing a rmdup in Samtools?
sequencing alignment samtools variant
updated 4 weeks ago by 36k • written 7.3 years ago by ▴ 350
2
votes
1
reply
2.6k
views
Estimating the expected number of reads that overlap a [heterozygous] snp in one window from the read depth, read length and resolution
statistics allele simualtion snp baf
updated 4 months ago by 36k • written 7.7 years ago by ▴ 350
6
votes
7
replies
2.2k
views
Why is the noise level higher in regions with amplification than regions with deletion in the genome?
dna-seq allele fraction tool snp noise
updated 6 months ago by 36k • written 7.9 years ago by ▴ 350
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