User: Alonzo

gravatar for Alonzo
Alonzo10
Reputation:
10
Status:
New User
Location:
United States
Last seen:
6 months, 3 weeks ago
Joined:
4 years, 1 month ago
Email:
l*********@gmail.com

Posts by Alonzo

<prev • 5 results • page 1 of 1 • next >
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Can limma/other DE algorithms be used for differential analysis of chemical descriptors?
... If I have two groups of small molecules with different properties, e.g. one can penetrate membranes and the other cannot, and I have an m × n matrix of m small molecules and n descriptors (e.g. polar surface area, molecular weight), can I use, say, limma to identify descriptors that differ between t ...
differential analysis cheminformatics limma edger written 6 months ago by Alonzo10 • updated 6 months ago by Devon Ryan88k
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How can I determine differential ubiquitination of a particular protein using CPTAC proteomics data?
... I want to check the ubiquitination of a specific protein, divide the samples into high and low ubiquitination levels of that protein, and then test other phenotypic differences between these two groups. The data is from CPTAC, and they have several mzML files as well as the original raw files for ea ...
proteomics ubiquitination post-translational cptac written 9 months ago by Alonzo10 • updated 8 months ago by pbpanigrahi180
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Can blind docking be used to determine which ligands are most likely to bind a known binding site?
... I know that blind docking is most often used to determine an unknown binding site, but can it be used to determine whether a ligand is thermodynamically more likely to bind a given (known) binding site instead of another site on the target protein? In other words, here's my thinking: if I dock a li ...
virtual screening vina blind docking written 17 months ago by Alonzo10
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Error When Reading GEO Series Matrix File Using GEOquery in R
... I'm running R 3.2.3 on Windows 8, trying to get phenotype data from a GSE using GEOquery (v. 2.36.0), but when I run the command `GSE781 <- getGEO(filename="GSE781--GPL96_series_matrix_txt.gz", GSEMatrix = TRUE)` I get the following error: `Error in xj[i]: only 0's may be mixed with negative ...
geo R bioconductor geoquery series matrix written 3.0 years ago by Alonzo10 • updated 2.9 years ago by Biostar ♦♦ 20
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Cell Biology Major with Almost No Computational Background Looking to Get into Bioinformatics Research
... Hey all, I'm a senior in college, majoring in cell biology. I got into research rather late (started summer just before my senior year), working in a wet lab under a post-doc who was studying biomarkers for metastasis in triple-negative breast cancer. I found that I really enjoyed the research proce ...
pure science senior cell biology pure biology written 4.1 years ago by Alonzo10 • updated 4.1 years ago by Josh Herr5.6k

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